If you are not a healthcare provider, click ‘Cancel’ and you will return to the Main Home page of the website to access more information about PADPeripheral Artery Disease, a potentially life threatening disease where plaque, like calcium, builds up along blood vessel walls, narrowing the arteries and reducing blood flow to the legs and feet. and how to Take A Stand Against AmputationTo surgically remove all or part of a limb (leg, foot or toe).